In collaboration with a Japanese research group the UCSD PEG researchers discover that the human loss of Siglec-14 reduces risk of chronic obstructive pulmonary disease (COPD) exacerbation. Their discovery has significant implications for prognosis and management of COPD.
Their paper is currently in press:
Angata, T., Ishii, T., Motegi, T., Oka, R., Taylor, R.E., Campos Soto, P., Chang, Y-C.,Secundino, I., Gao, C-X., Ohtsubo, K., Kitazume, S., Nizet, V., Varki, A., Gemma, A., Kida, K., Taniguchi, N.: Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation. Cell Mol Life Sci., 2013.
Link to journal: http://link.springer.com/journal/18