Biological Roles of Glycans

Varki A. Glycobiology. 2016 Aug 24. pii: cww086. [Epub ahead of print] Review. PMID: 27558841 Abstract Simple and complex carbohydrates (glycans) have long been known to play major metabolic, structural and physical roles in biological systems. Targeted microbial binding to host glycans … Continued

Evolutionary inactivation of a sialidase in group B Streptococcus

Yamaguchi M, Hirose Y, Nakata M, Uchiyama S, Yamaguchi Y, Goto K, Sumitomo T, Lewis AL, Kawabata S, Nizet V. Sci Rep. 2016 Jun 29;6:28852. doi: 10.1038/srep28852. PMID: 27352769 Abstract Group B Streptococcus (GBS) is a leading cause of bacterial sepsis and … Continued