Hyperglycemia diverts dividing stem cells to pathological adipogenesis

Hascall V, Wang A. Stem Cell Res Ther. 2014 Nov 17;5(6):128. doi: 10.1186/scrt518. PMID: 25689074

This commentary proposes a mechanism for why murine diabetic adipose tissue contains very few remaining stem cells compared with normal adipose tissue. The mechanism involves the diversion of stem cells to pathological adipocytes when they divide in hyperglycemia.