Elevated pulmonary pressure: A novel risk marker in kidney disease?

Navaneethan SD, Dweik RA. Kidney Int. 2015 Jul;88(1):7-9. doi: 10.1038/ki.2015.111. PMID: 26126087 Abstract Pulmonary hypertension is associated with adverse cardiac outcomes and death in the general population. Bolignano and colleagues studied the prevalence of higher estimated pulmonary artery systolic pressure (⩾35 mm Hg) assessed … Continued

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation

Nandadasa S, Nelson CM, Apte SS. Cell Rep. 2015 Jun 16;11(10):1519-28. doi: 10.1016/j.celrep.2015.05.005. PMID: 26027930 Abstract Despite the significance for fetal nourishment in mammals, mechanisms of umbilical cord vascular growth remain poorly understood. Here, the secreted metalloprotease ADAMTS9 is shown to be … Continued

The role of hyaluronan in innate defense responses of the intestine

de la Motte CA, Kessler SP. Int J Cell Biol. 2015;2015:481301. doi: 10.1155/2015/481301. Review. PMID: 25922605 Abstract Hyaluronan is an abundant extracellular matrix component prevalent in the vertebrate intestinal tract. Here we discuss what is known about hyaluronan distribution during homeostasis and … Continued