Aiyetan P, Zhang B, Chen L, Zhang Z, Zhang H.(2014) M2Lite: An Open-source, Light-weight, Pluggable and Fast Proteome Discoverer MSF to mzIdentML Tool. J Bioinform. 1(2):40-49. PMID: 25346941. PMCID: PMC4206089.
Proteome Discoverer is one of many tools used for protein database search and peptide to spectrum assignment in mass spectrometry-based proteomics. However, the inadequacy of conversion tools makes it challenging to compare and integrate its results to those of other analytical tools. Here we present M2Lite, an open-source, light-weight, easily pluggable and fast conversion tool. M2Lite converts proteome discoverer derived MSF files to the proteomics community defined standard – the mzIdentML file format. M2Lite’s source code is available as open-source at https://bitbucket.org/paiyetan/m2lite/src and its compiled binaries and documentation can be freely downloaded at https://bitbucket.org/paiyetan/m2lite/downloads.
KEYWORDS: Bioinformatics; IDPicker; MSF; Peptide identification; Proteome Discoverer; Proteomics; mzIdentML; pepXML
Link to journal: http://www.jclinbioinformatics.com/